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Background and history

We are a consultancy providing technical advice and services in antibody humanization, antibody design and antibody structure determination. We also offer expert advice on scientific aspects of antibody intellectual property issues.

We have more than 30 years of experience in antibody modeling and antibody engineering. With numerous collaborators we have made key discoveries in the areas of variable region modeling, affinity improvement by protein engineering, analysis of the topologies of antibody combining sites and humanization by 'resurfacing' and 'superhumanization'. Our antibody web-modeling software WAM, now unfortunately no longer operational, was one of the most widely used methods for modeling variable regions of antibodies during the past 20 years.

The Antibody Molecule

Available Now

The Antibody Molecule

A detailed history of antibody discovery from Jenner to the present day.

Anthony R. Rees

Published: 30 October 2014 (UK), 2 January 2015 (USA),
1 March 2015 (e-book). Oxford University Press


Find out more (UK)   Find out more (USA)

RCAB is a fee-for-service company and welcomes enquiries on any aspect of antibody structure and design. Contact us at

© Rees Antibody Consulting AB | Organisation number: 556972-6879 | Nas Focksta 19,75591 Uppsala, Sweden